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A Guide to Metafolin® in Hipp Organic Baby Formula

HiPP infant nutrition is a trusted name in the baby formula business, this family-owned business stretching back across four generations. They don't just provide infant nutrition; their ongoing research strives to reproduce breast milk as closely as possible. This dedication has seen them pioneer the introduction of Metafolin®, which now can be found in all their Combiotic product lines.

What is Metafolin®?

Metafolin® is a patented form of folic acid that is made using a unique manufacturing process. Unlike regular folic acid, which is synthesized in a laboratory, Metafolin® is derived from natural sources and is more easily absorbed by the body. This means that it is more bioavailable to babies, and can provide them with the benefits of folic acid in a more effective and efficient way.

Why is folic acid important for babies?

Folid Acid Organic Formula Shop

It helps to support the formation of red blood cells, the proper functioning of the nervous system, and the growth of cells and tissues. Additionally, folic acid is important for the development of the baby's brain, spinal cord, and skull.

During pregnancy, folic acid is especially important for preventing birth defects, such as neural tube defects. For this reason, pregnant women are often advised to take a folic acid supplement. However, even after birth, babies still need folic acid to support their growth and development.

Folid Acid vs Metafolin®

To discover the safety of Metafolin® fortified formula, a study showed that babies who received this folate form were nourished just like those breastfed. Plus, their folate levels were up-to-par with infants from the control group too! All in all, every baby could benefit significantly from formulas already containing bioactive folic acid.

Ingredient Fact:
Folic acid/folate comes from the Latin 'folium' (leaf). This is because the first sources of vitamin B were extracted from spinach leaves.

How is Metafolin® used in Hipp Organic Baby formula?

HiPP Combiotik infant formulas contain folate, an important B vitamin essential for cell division and growth. During your baby's rapid physical development, this nutrient supplies the necessary components to synthesize purine and pyrimidine that provide structure for DNA & RNA molecules. Folate is crucial for cell division and tissue growth; it supports the following:

  • DNA synthesis
  • Cell division
  • Blood formation
  • Protein synthesis

This vitamin is, therefore, indispensable for brain development, growth, and blood formation, especially in the early stages of development.

folid acid vs metafolin


Natural Folate Source
For many years, synthetic folic acid was the only option available in baby formula, but not anymore. Thanks to recent research revealing that breastfeeding provides babies with Metafolin® (5-MTHF), HiPP has taken a significant step forward by adding an unprecedented source of natural folate to their formulas. Metafolin® is readily available to the body. Synthetic folic acid requires a great deal of effort to be absorbed as it must first be 'activated' in the body before it can be effective. Folate or Metafolin®, on the other hand, can be absorbed easily, and all babies can process Metafolin® immediately. Thanks to the natural folate source Metafolin®, easy absorption and processing of this vital vitamin is guaranteed. 

Furthermore, Metafolin® has been approved by the European Food Safety Authority (EFSA). An extensive clinical trial supports its suitability and demonstrates age-appropriate physical growth in infants.

Why choose Hipp organic baby formula with Metafolin®?

Hipp organic baby formula with Metafolin

Choosing a baby formula that contains Metafolin® has a number of benefits for babies and their parents. By providing a more easily absorbed form of folic acid, Hipp organic baby formula with Metafolin® can help to ensure that babies get the benefits of folic acid in a more effective and efficient way. Additionally, because Hipp organic baby formula is made using only the best organic ingredients, parents can feel confident that they are providing their babies with a high-quality, nutritious formula that supports their health and well-being. By ordering this formula, parents can ensure that their newborns get optimal amounts of Metafolin® for healthy growth and development when they need it most.


Metafolin® is a unique ingredient found in some types of organic baby formula, including Hipp organic baby formula. By providing a more easily absorbed form of folic acid, Metafolin® helps to ensure that babies get the benefits of folic acid in a more effective and efficient way. When choosing a baby formula, parents should look for formulas that contain Metafolin® and other high-quality, organic ingredients to support their baby's health and well-being.

Not sure which formula to order?
Please check our baby formula comparison chart to help you understand the differences between our offered formulas. 
Please know that we have a dedicated parent support team who are ready to answer your questions. Please shoot us an email at, and we'll get back to you shortly. We are here to help!

Please note: every person and situation is different so we always advise you to talk to your pediatrician first and see how these guidelines and tips can help you. This guide is not a substitute for professional medical advice, diagnosis, or treatment.